HSPD1 recombinant monoclonal antibody, clone HSPD1/2206R

Western Blot (Cell lysate)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Entrez GeneID

Protein Accession#

Gene Name

HSPD1

Gene Alias

CPN60, GROEL, HLD4, HSP60, HSP65, HuCHA60, SPG13

Gene Description

heat shock 60kDa protein 1 (chaperonin)

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq

Other Designations

P60 lymphocyte protein|chaperonin|heat shock 60kD protein 1 (chaperonin)|heat shock protein 65|mitochondrial heat shock 60kD protein 1 variant 1|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1|spastic paraplegia 13 (autosomal dominant)