FRAT 3 (Frequently Rearranged in Advanced T-cell Lymphomas 3, Peg12, Paternally Expressed 12)

Cat# F6092-26-100ug

Size : 100ug

Brand : US Biological



F6092-26 Rabbit Anti-FRAT 3 (Frequently Rearranged in Advanced T-cell Lymphomas 3, Peg12, Paternally Expressed 12)

Clone Type
Polyclonal
Host
goat
Source
mouse
Isotype
IgG
Grade
Affinity Purified
Crossreactivity
Mo
Accession #
NP_038816.1
Shipping Temp
Blue Ice
Storage Temp
-20°C

FRAT 3 (Principal Names -Peg12, Frat3, paternally expressed 12, frequently rearranged in advanced T-cell lymphomas 3 Official Gene Symbol-Peg12GenBank Accession Number NP_038816 LocusLink ID-27412 (mouse)) is directed against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues. FRAT3/Peg12 is expressed primarily is embryonic stages and is an inhibitor of GSK-3 activity in the Wnt signaling pathway. FRAT3 has also been linked to Prader-Willi syndrome in mice.||Applications:|Suitable for use in ELISA. Other applications not tested.||Recommended Dilution:|ELISA: 1:2000|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: goat|Source: mouse|Concentration: ~0.5mg/ml|Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.|Purity: Purified by affinity chromatography.|Immunogen: Synthetic peptide corresponding to C-SLAANNPGGHSTNL from the C Terminus of PEG12/FRAT3 (NP_038816.1).|Specificity: Recognizes PEG12/FRAT3. Sequence homology: mouse.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide corresponding to C-SLAANNPGGHSTNL from the C Terminus of PEG12/FRAT3 (NP_038816.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Purity
Purified by affinity chromatography.
Specificity
Recognizes PEG12/FRAT3. Sequence homology: mouse.
References
1. Kobayashi S, Kohda T, Ichikawa H, Ogura A, Ohki M, Kaneko-Ishino T, Ishino F. Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region. Biochem Biophys Res Commun. 2002 Jan 11;290(1):403-8. PMID: 11779183