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Flow Cytometry
Flow cytometric analysis of K562 cells with EGFR (phospho Y1068) monoclonal antibody, clone E5 (APC) (Cat # MAB18886). Unstained cells negative control (blue) or stained and untreated (red) or treated with EGF and pervanadate (green).
- Specifications
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human EGFR.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y1068 of human EGFR.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Conjugation
APC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Flow Cytometry
Flow cytometric analysis of K562 cells with EGFR (phospho Y1068) monoclonal antibody, clone E5 (APC) (Cat # MAB18886). Unstained cells negative control (blue) or stained and untreated (red) or treated with EGF and pervanadate (green). - Gene Info — EGFR
Entrez GeneID
1956Gene Name
EGFR
Gene Alias
ERBB, ERBB1, HER1, PIG61, mENA
Gene Description
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor
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