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Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western Blot (cell lysate) analysis of U-937 cell lysate.

  • Specifications

    Product Description

    Rabbit monoclonal antibody raised against synthetic protein of human CES1.

    Immunogen

    A synthetic peptide corresponding to human CES1.

    Host

    Rabbit

    Reactivity

    Human

    Specificity

    This antibody reacts with human, mouse, rat CES1, in native form and recombinant. Superfamily members of CES1 are not reactive to antibody.

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Western Blot (1:1000-5000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western Blot (cell lysate) analysis of U-937 cell lysate.
  • Gene Info — CES1

    Entrez GeneID

    1066

    Protein Accession#

    P23141

    Gene Name

    CES1

    Gene Alias

    ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH

    Gene Description

    carboxylesterase 1 (monocyte/macrophage serine esterase 1)

    Omim ID

    114835

    Gene Ontology

    Hyperlink

    Gene Summary

    Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    acyl coenzyme A:cholesterol acyltransferase|carboxylesterase 1|carboxylesterase 2 (liver)|cholesteryl ester hydrolase|egasyn|liver carboxylesterase|triacylglycerol hydrolase

  • Interactomes
  • Pathways
  • Diseases