Biotin-PEG4-alkyne [1458576-00-5]
Cat# HY-140922-50mg
Size : 50mg
Brand : MedChemExpress
Description |
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. |
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IC50 & Target |
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In Vitro |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |