General Info
Applications: | ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.125ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This ADCY10 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Adcy10 |
Gene ID: | 59320 |
Uniprot ID: | ADCYA_RAT |
Sample Type: | tissue homogenates or other biological fluids. |
Description
Tissue Specificity | Detected in testis (at protein level). Preferentially expressed in testis. |
Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
Protein Name | Adenylate Cyclase Type 10 Germ Cell Soluble Adenylyl Cyclase Sac Testicular Soluble Adenylyl Cyclase |
Database Links | Reactome: R-RNO-5610787 |
Cellular Localisation | Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Perinuclear Region Nucleus Cell Projection Cilium Mitochondrion Distributed To Subcellular Compartments Containing Camp Targets Found As A Plasma Membrane-Associated Protein Protein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
Alternative ELISA Names | Adenylate Cyclase Type 10 ELISA kit Germ Cell Soluble Adenylyl Cyclase ELISA kit Sac ELISA kit Testicular Soluble Adenylyl Cyclase ELISA kit Adcy10 ELISA kit Sac ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance