Streptomycin (sulfate) [3810-74-0]
Cat# HY-B0472-10g
Size : 10g
Brand : MedChemExpress
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.
For research use only. We do not sell to patients.
Streptomycin sulfate Chemical Structure
CAS No. : 3810-74-0
This product is a controlled substance and not for sale in your territory.
Based on 18 publication(s) in Google Scholar
Other Forms of Streptomycin sulfate:
- Streptomycin In-stock
View All Antibiotic Isoform Specific Products:
Description |
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis. |
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IC50 & Target |
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In Vitro |
Strain RB1 shows enhanced susceptibility to streptomycin as the concentration of CV in the growth medium increases. As the CV concentration in the growth medium increases, both cytochrome aa3 levels and streptomycin susceptibility increase. Cytochrome aa3 is necessary for accumulation of streptomycin by B. subtilis[1]. Streptomycin influences tRNA selection. Streptomycin resistance mutations generally map to protein S12 and most of these variants exhibit increased levels of discrimination in the tRNA selection process[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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Molecular Weight |
728.69 |
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Formula |
C21H42N7O18S1.5 |
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CAS No. |
3810-74-0 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O[C@@]1(C=O)[C@H]([C@@H](O[C@H]1C)O[C@]([C@@H]([C@@H](O)[C@@H]2NC(N)=N)O)(17)[C@H]([C@@H]2O)NC(N)=N)O[C@@](O[C@@H](CO)[C@H](O)[C@H]3O)(17)[C@H]3NC.[1.5H2SO4] |
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Structure Classification |
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Initial Source |
Streptomyces |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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Solvent & Solubility |
In Vitro:
H2O : ≥ 100 mg/mL (137.23 mM) DMSO : < 1 mg/mL (insoluble or slightly soluble) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: ≥98.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O | 1 mM | 1.3723 mL | 6.8616 mL | 13.7233 mL | 34.3081 mL |
5 mM | 0.2745 mL | 1.3723 mL | 2.7447 mL | 6.8616 mL | |
10 mM | 0.1372 mL | 0.6862 mL | 1.3723 mL | 3.4308 mL | |
15 mM | 0.0915 mL | 0.4574 mL | 0.9149 mL | 2.2872 mL | |
20 mM | 0.0686 mL | 0.3431 mL | 0.6862 mL | 1.7154 mL | |
25 mM | 0.0549 mL | 0.2745 mL | 0.5489 mL | 1.3723 mL | |
30 mM | 0.0457 mL | 0.2287 mL | 0.4574 mL | 1.1436 mL | |
40 mM | 0.0343 mL | 0.1715 mL | 0.3431 mL | 0.8577 mL | |
50 mM | 0.0274 mL | 0.1372 mL | 0.2745 mL | 0.6862 mL | |
60 mM | 0.0229 mL | 0.1144 mL | 0.2287 mL | 0.5718 mL | |
80 mM | 0.0172 mL | 0.0858 mL | 0.1715 mL | 0.4289 mL | |
100 mM | 0.0137 mL | 0.0686 mL | 0.1372 mL | 0.3431 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Streptomycin sulfate Related Classifications
- Infection
- Anti-infection
- Bacterial Antibiotic