- More Files
- Specifications
Product Description
HDAC2 Assay Kit is use for measuring the amount of HDAC2.
Regulation Status
For research use only (RUO)
Storage Instruction
Store HB5 and HDAC2 control at -20°C. Store HB1, HB3, HB4, HB6 and 8 well strips at 4°C away from light. Store all other components at room temperature.
- Applications
Quantification
- Gene Info — HDAC2
Entrez GeneID
3066Gene Name
HDAC2
Gene Alias
RPD3, YAF1
Gene Description
histone deacetylase 2
Omim ID
605164Gene Ontology
HyperlinkGene Summary
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq
Other Designations
OTTHUMP00000040427|YY1-associated factor 1|transcriptional regulator homolog RPD3
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Role of statins and mevalonate pathway on impaired HDAC2 activity induced by oxidative stress in human airway epithelial cells.
Matera MG, Calzetta L, Gritti G, Gallo L, Perfetto B, Donnarumma G, Cazzola M, Rogliani P, Donniacuo M, Rinaldi B.
European Journal of Pharmacology 2018 Aug; 832:114.
Application：Quant, Human, Nuclear lysate from A549 cells.
- Role of statins and mevalonate pathway on impaired HDAC2 activity induced by oxidative stress in human airway epithelial cells.