Reagents and instruments for immunology, cell biology and molecular biology.

CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A, MGC117044) (Biotin)

Print

Cat# C2262-36-Biotin-100ul

Size : 100ul

Brand : US Biological

Request more information

C2262-36-Biotin CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A, MGC117044) (Biotin)

Clone Type

Polyclonal

Host

mouse

Source

human

Swiss Prot

P11215

Isotype

IgG1,k

Grade

Purified

Applications

FC IHC

Crossreactivity

Hu Mk Po

Shipping Temp

Blue Ice

Storage Temp

-20°C

Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 ( alphaMBeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B).||Applications:|Suitable for use in Immunohistochemistry, Flow Cytometry and Blocking Studies. Other applications not tested. ||Recommended Dilution:|Immunohistochemistry: frozen|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications

Product Type: Mab|Isotype: IgG1,k|Clone No: ICRF44|Host: mouse|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.|Purity: Purified|Immunogen: Rheumatoid synovial cells and human monocytes|Specificity: Recognizes human CD11b. Species Crossreactivity: Porcine, Rhesus. Cynomolgus, Chimpanzee and Baboon||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Immunogen

Rheumatoid synovial cells and human monocytes

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity

Purified

Specificity

Recognizes human CD11b. Species Crossreactivity: Porcine, Rhesus. Cynomolgus, Chimpanzee and Baboon

References

1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford.|2. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford.|3. Springer, T.A. 1994. Cell 76:301.|4. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD11b Section, Academic Press, New York, p. 158.|5. Lee, J.O., L.A. Bankston, M.A. Arnaout, and R.C. Liddington. 1995. Structure 3:1333.|6. Zhang, L.., and E.F. Plow. 1996. J. Biol. Chem. 271:18211.|7. Davis, G.E. 1992. Exp. Cell. Res. 200:242.|8. Perry, H.R., and R.F. Todd, III. 1996. Immunol. Today 17:209.