Specifications
- Features Potent Inhibitor of PDE7
- Induces apoptosis
- Cell permeable
- Room temperature storage
Images
BRL-50481 is a potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B. Increases mineralization in osteoblasts differentiated from hMSC. Cell permeable.