BAY-2965501 is a first-in-class a diacylglycerol kinase zeta (DGKζ, lipid kinase) inhibitor with IC50 of 27 nM/35 nM (human/mouse) and shows > 20-fold selectivity for DGKζ over other DGK isotypes. BAY-2965501 blocks DGKζ in T-cells to activate them [[2732902-08-6]]
Cat# orb1910863-1g
Size : 1g
Brand : Biorbyt
BAY-2965501
Catalog Number: orb1910863
Catalog Number | orb1910863 |
---|---|
Category | Small Molecules |
Description | BAY-2965501 is a first-in-class a diacylglycerol kinase zeta (DGKζ, lipid kinase) inhibitor with IC50 of 27 nM/35 nM (human/mouse) and shows > 20-fold selectivity for DGKζ over other DGK isotypes. BAY-2965501 blocks DGKζ in T-cells to activate them |
CAS Number | [2732902-08-6] |
MW | 414.45 |
SMILES | C1C=C(C=CC=1OC)C(C1SC(N([C@@H](C(N)=O)C)C2C=CC(=CC=2)F)=NC=1N)=O |
Formula | C20H19FN4O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |