Recombinant Ovine IL-4
Cat# RP1130V-005
Size : 5ug
Brand : Kingfisher Biotech
Bulk quantities of Ovine (Sheep) IL-4 protein are available.
Please for pricing.
Ovine (Sheep) IL-4 Specifications
Molecular Weight (calculated) - 12.6kDa
Amino Acid Sequence - HKCDITLEEI IKTLNILTSR KNSCMELPVA DVFAAPKNAT EKETFCRAGI ELRRIYRSHM CLNKFLGGLD RNLSSLASKT CSVNEAKTST STLRDLLERL KTIMKEKYSK C (111)
Gene ID - 443327
Homology Across Species
Ovis aries (sheep) IL-4 – 100%
Capra hircus (goat) IL-4 – 99%
Oryx dammah (scimitar-horned oryx) IL-4 – 98%
More - https://blast.ncbi.nlm.nih.gov/
Endotoxin - Naturally endotoxin-free
Applications
Cell Culture, ELISA Standard, Western Blot Control
IL-4 Background
Interleukin-4 (IL-4) induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. Upon activation by IL-4, Th2 cells subsequently produce additional IL-4. IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. IL-4 induces B-cell class switching to IgE, and up-regulates MHC class II production. Overproduction of IL-4 is associated with allergies.
Alternate Names - IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4, interleukin 4
