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> MLL5 antibody

MLL5 antibody

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Cat# orb66810-100ul

Size : 100ul

Brand : Biorbyt


    MLL5 antibody

    Catalog Number: orb66810

    Catalog Numberorb66810
    CategoryAntibodies
    DescriptionRabbit polyclonal to MLL5.MLL5 is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family. It is a histonemethyltransferase that specifically mono-and dimethylates Lys-4 of histone H3 (H3K4me1 andH3K4me2). Lys-4 methylation of H3 represents a specific tag for epigenetic transcriptional activation.It is a key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulationof hematopoietic stem cell self-renewal by a mechanism that involves DNA methylation.Overexpression of MLL5 inhibits cell cycle progression while knockdown induces cell cycle arrest atboth the G1 and G2/M phases.
    Species/HostRabbit
    ClonalityPolyclonal
    Tested applicationsWB
    ReactivityHuman
    ImmunogenN-terminal region of human MLL5
    Dilution rangeWB:1:1000-1:5000
    PurityAffinity purification
    ConjugationUnconjugated
    MW205
    UniProt IDQ8IZID2
    Storage-20°C
    Buffer/Preservatives0.01% NaN3
    Alternative namesanti-MLL5 antibody,anti-FLJ10078 antibody,anti-FLJ
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    MLL5 antibody

    Western blot analysis of total cell extracts from human Hela using MLL5 antibody