- More Files
- Specifications
Product Description
Mouse recombinant monoclonal antibody raised against human LTA.
Antibody Species
Mouse
Immunogen
Original antibody is raised against purified recombinant human LTalpha expressed in Escherichia coli.
Reactivity
Human
Form
Liquid
Isotype
IgG2b kappa
Recommend Usage
ELISA
Flow Cytometry
Neutralization
Surface Plasmon Resonance
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. - Applications
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Neutralization
Surface Plasmon Resonance
- Gene Info — LTA
Entrez GeneID
4049Gene Name
LTA
Gene Alias
LT, TNFB, TNFSF1
Gene Description
lymphotoxin alpha (TNF superfamily, member 1)
Omim ID
153440Gene Ontology
HyperlinkGene Summary
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
Other Designations
OTTHUMP00000029184|OTTHUMP00000037612|OTTHUMP00000037613|OTTHUMP00000165897|lymphotoxin alpha|tumor necrosis factor beta
- Interactomes
- Pathways
- Diseases