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> HMBR [1287651-36-8]

HMBR [1287651-36-8]

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Cat# HY-D1416-5mg

Size : 5mg

Brand : MedChemExpress


HMBR, an analog bearing an additional methyl group on the aromatic ring, is nonfluorescent by itself, but it fluoresces yellow light upon blue-light excitation when bound to Y-FAST. HMBR is nontoxic for zebrafish embryos. cell-permeant.

For research use only. We do not sell to patients.

HMBR Chemical Structure

HMBR Chemical Structure

CAS No. : 1287651-36-8

This product is a controlled substance and not for sale in your territory.

Based on 1 publication(s) in Google Scholar

Description

HMBR, an analog bearing an additional methyl group on the aromatic ring, is nonfluorescent by itself, but it fluoresces yellow light upon blue-light excitation when bound to Y-FAST. HMBR is nontoxic for zebrafish embryos. cell-permeant[1].

Molecular Weight

251.32

Formula

C11H9NO2S2
CAS No.

1287651-36-8
Appearance

Solid

Color

Yellow to orange

SMILES

S=C(NC/1=O)SC1=C/C2=CC(C)=C(C=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (497.37 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9790 mL 19.8950 mL 39.7899 mL
5 mM 0.7958 mL 3.9790 mL 7.9580 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.34%

COA (250 KB) HNMR (240 KB) LCMS (268 KB)

Handling Instructions (2659 KB)
References

  • [1]. Plamont MA, et al. Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo [published correction appears in Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1412. Moncoq, Karine [added]]. Proc Natl Acad Sci U S A. 2016;113(3):497-502.  [Content Brief]

  • [1]. Plamont MA, et al. Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo [published correction appears in Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1412. Moncoq, Karine [added]]. Proc Natl Acad Sci U S A. 2016;113(3):497-502.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9790 mL 19.8950 mL 39.7899 mL 99.4748 mL
5 mM 0.7958 mL 3.9790 mL 7.9580 mL 19.8950 mL
10 mM 0.3979 mL 1.9895 mL 3.9790 mL 9.9475 mL
15 mM 0.2653 mL 1.3263 mL 2.6527 mL 6.6317 mL
20 mM 0.1989 mL 0.9947 mL 1.9895 mL 4.9737 mL
25 mM 0.1592 mL 0.7958 mL 1.5916 mL 3.9790 mL
30 mM 0.1326 mL 0.6632 mL 1.3263 mL 3.3158 mL
40 mM 0.0995 mL 0.4974 mL 0.9947 mL 2.4869 mL
50 mM 0.0796 mL 0.3979 mL 0.7958 mL 1.9895 mL
60 mM 0.0663 mL 0.3316 mL 0.6632 mL 1.6579 mL
80 mM 0.0497 mL 0.2487 mL 0.4974 mL 1.2434 mL
100 mM 0.0398 mL 0.1989 mL 0.3979 mL 0.9947 mL
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HMBR Related Classifications

  • Others
  • Others
  • Fluorescent Dye
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HMBR1287651-36-8Fluorescent Dyeyellow lightY-FASTnontoxiccell-permeantInhibitorinhibitorinhibit