Bovine IL-1 alpha Polyclonal Antibody - Biotinylated

Cat# PBB0332B-050

Size : 50ug

Brand : Kingfisher Biotech

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The IL-1 family of cytokines encompasses eleven proteins that each share a similar β-barrel structure and bind to Ig-like receptors. Several of the well characterized members of the IL-1-like cytokines play key roles in the development and regulation of inflammation. IL-1α (IL-1F1), IL-1β (IL-1F2), and IL-18 (IL-1F4) are well-known inflammatory cytokines active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. In contrast, IL-1 receptor antagonist (IL-1ra; IL-1F3) and IL-36 receptor antagonist (IL-36ra; IL-1F5) reduce inflammation by blocking the binding of the agonist receptor ligands. IL-33 (IL-1F11) is thought to function as an 'alarmin' released following cell necrosis to alerting the immune system to tissue damage or stress.

Reactivity - ELISA
Bovine IL-1 alpha - Strong
Canine IL-1 alpha - Weak
Dolphin IL-1 alpha - None
Equine IL-1 alpha - Moderate
Feline IL-1 alpha - Weak
Rabbit IL-1 alpha - None

Catalog No.:
PBB0332B-050
Quantity:
50 ug
Alias:
IL-1F1
Country of Origin:
USA
Host:
The bovine IL-1 alpha polyclonal antibody was produced in rabbits.
Purification:
Antigen-affinity Purification
Immunogen:
Recombinant Bovine IL-1 alpha
Applications:
The bovine IL-1 alpha polyclonal antibody has been qualified for use in Western Blot and ELISA applications.