Reagents and instruments for immunology, cell biology and molecular biology.
 
> Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-111)-PE Conjugated

Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-111)-PE Conjugated

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Cat# 30-2176-100

Size : 100Testss

Brand : Abeomics

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Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-111)-PE Conjugated

Figure 1: Western blottin analysis of CD54 expression in TNF-alpha activated (A) and nonactivated (B) HUVEC cells by antibody MEM-111. Lower bands represent tubulin as a loading control.

Amount : 100 tests
Isotype : Mouse IgG2a
Storage condition : Store in the dark at 2-8px ! important;width:210px">
Gene : ICAM1
Gene ID : 3383
Uniprot ID : P05362
Alternative Name : ICAM1
Immunogen Information : Raji human Burkitt's lymphoma cell line
CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
Subcellular location: Membrane
Post transnational modification: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
BioGrid: 109610. 178 interactions.
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