Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-APC Conjugated

Cat# 30-1669-100

Size : 100Testss

Brand : Abeomics


Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-APC Conjugated



Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : TNFRSF9
Gene ID : 3604
Uniprot ID : Q07011
Alternative Name : TNFRSF9, CD137, ILA
Immunogen Information : Recombinant human CD137 ectodomain
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
Subcellular location: Membrane
Tissue Specificity: Expressed on the surface of activated T-cells.
BioGrid: 109817. 13 interactions.
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Description
Cond.
Price Bef. VAT
NB-47-05100-100TESTS
 100TESTS/1ml