Anti-bovine CD47 monoclonal antibody (clone HUH71A)

Background

CD47, also known as integrin associated protein (IAP), belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP alpha). CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. CD47 is ubiquitously expressed in human cells and has found to be overexpressed in many different tumor cells.

Specifications

Clone - HUH71A

Isotype - IgG1

Host - Mouse

Known Reactivity - Bison, Bovine, Caprine, Human, Ovine

Purification - Anti-bovine CD47 monoclonal antibody, clone HUH71A, was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.

Alternate Names -