3-Hydroxyhippuric acid [1637-75-8]
Cat# HY-113085-50mg
Size : 50mg
Brand : MedChemExpress
3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.
For research use only. We do not sell to patients.
3-Hydroxyhippuric acid Chemical Structure
CAS No. : 1637-75-8
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Description |
3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. |
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IC50 & Target |
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Molecular Weight |
195.17 |
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Formula |
C9H9NO4 |
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CAS No. |
1637-75-8 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C(O)CNC(C1=CC=CC(O)=C1)=O |
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Structure Classification |
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Initial Source |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
DMSO : 83.33 mg/mL (426.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO
+
%
+
%
Tween-80
+
%
Saline
The co-solvents required include: DMSO,
. All of co-solvents are available by MedChemExpress (MCE).
, Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration:
mg/mL
Method for preparing stock solution:
mg
drug dissolved in
μL
DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take
μL DMSO stock solution, add
μL .
μL , mix evenly, next add
μL Tween 80, mix evenly, then add
μL Saline.
If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
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Purity & Documentation |
Purity: 99.83% |
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO | 1 mM | 5.1237 mL | 25.6187 mL | 51.2374 mL | 128.0935 mL |
5 mM | 1.0247 mL | 5.1237 mL | 10.2475 mL | 25.6187 mL | |
10 mM | 0.5124 mL | 2.5619 mL | 5.1237 mL | 12.8093 mL | |
15 mM | 0.3416 mL | 1.7079 mL | 3.4158 mL | 8.5396 mL | |
20 mM | 0.2562 mL | 1.2809 mL | 2.5619 mL | 6.4047 mL | |
25 mM | 0.2049 mL | 1.0247 mL | 2.0495 mL | 5.1237 mL | |
30 mM | 0.1708 mL | 0.8540 mL | 1.7079 mL | 4.2698 mL | |
40 mM | 0.1281 mL | 0.6405 mL | 1.2809 mL | 3.2023 mL | |
50 mM | 0.1025 mL | 0.5124 mL | 1.0247 mL | 2.5619 mL | |
60 mM | 0.0854 mL | 0.4270 mL | 0.8540 mL | 2.1349 mL | |
80 mM | 0.0640 mL | 0.3202 mL | 0.6405 mL | 1.6012 mL | |
100 mM | 0.0512 mL | 0.2562 mL | 0.5124 mL | 1.2809 mL |
3-Hydroxyhippuric acid Related Classifications
- Others
- Metabolic Enzyme/Protease
- Endogenous Metabolite