α-MSH (TFA) [171869-93-5]
Cat# HY-P0252A-10mg
Size : 10mg
Brand : MedChemExpress
Description |
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC)[1][2]. |
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IC50 & Target |
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In Vitro |
α-MSH TFA modulates CNS inflammation by acting directly on melanocortin receptors in glial cells. α-MSH TFA modulates NFκB activation. α-MSH TFA inhibits translocation of transcription factor κB to the nucleus[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |