• Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of TMED10.

    Immunogen

    A synthetic peptide corresponding to amino acids 100-200 of human TMED10.

    Host

    Rabbit

    Reactivity

    Bovine, Human, Mouse, Primates, Rabbit, Rat

    Specificity

    This antibody is useful for Western blot analysis where a band is seen at ~21 KDa.

    Form

    Liquid

    Conjugation

    Biotin

    Recommend Usage

    Western Blot (2 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS

    Storage Instruction

    Store at 4°C. Do not freeze.

  • Applications

    Western Blot

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

  • Gene Info — TMED10

    Entrez GeneID

    10972

    Protein Accession#

    P49755

    Gene Name

    TMED10

    Gene Alias

    P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I

    Gene Description

    transmembrane emp24-like trafficking protein 10 (yeast)

    Omim ID

    605406

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq

    Other Designations

    21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10

  • Interactomes
  • Diseases