Size : 10mM(in1mLH2O)
Request more information
Please log in to use this feature.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
L-Glutathione Reduced is an endogenous antioxidant, with the ability to scavenge oxygen-derived free radicals. L-Glutathione Reduced is a non-protein thiol widely present in living cells, which plays an important role in a series of biological events, including protein and DNA synthesis, enzyme activity, metabolism as well as cell protection. Not only does L-Glutathione Reduced scavenge oxygen-derived free radicals which contribute to the development of many common diseases including cancer, heart attack, stroke, arthritis, but it also helps in regenerating other antioxidants such as vitamin E and ascorbic acid. Thus, L-Glutathione Reduced is established to be a marker of oxidative stress. In addition, L-Glutathione Reduced is used for eluting glutathione S-transferase (GST) from glutathione agarose.
Reference:
1. Pereira-Rodrigues N, Cofré R, Zagal JH, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry, 2007, 70(1): 147-154.
Animal models
Male Hypothyroidism Wistar rats
Dosage form
0.0012%, oral administration
Application
Compared with the control group, no significant effects were observed in the rates of lipid peroxidation and vitamin E in hepatic and cardiac tissues of hypothyroidism rats, while the thyroid function of hyperthyroidism rats was significantly enhanced.
Other notes
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal.
References:
[1]. Messarah M, Boulakoud MS, Boumendjel A, Abdennour C, El Feki A. The impact of thyroid activity variations on some oxidizing-stress parameters in rats. C R Biol. 2007 Feb;330(2):107-12. Epub 2006 Dec 12. PubMed PMID: 17303537.
