IRX3, NT (IRX3, IRXB1, Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3) (FITC)

Cat# 037114-FITC-200ul

Size : 200ul

Brand : US Biological

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037114-FITC IRX3, NT (IRX3, IRXB1, Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3) (FITC) discontinued

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
P78415
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA IHC WB
Crossreactivity
Hu Xe
Accession #
NP_077312.2; P78415; O42261; P81067
Gene #
IRX3
Shipping Temp
Blue Ice
Storage Temp
-20°C

IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).||Applications:|Suitable for use in Western Blot, Immunohistochemistry and FLISA. Other applications have not been tested.||Recommended Dilutions:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).|Purity: Purified by Protein A affinity chromatography.|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 111-140 in the N-terminal region of human IRX3, UniProt Accession #NP_077312.2; P78415; O42261; P81067. |Specificity: Recognizes human IRX3. Species Crossreactivity: Xenopus||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 111-140 in the N-terminal region of human IRX3, UniProt Accession #NP_077312.2; P78415; O42261; P81067.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human IRX3. Species Crossreactivity: Xenopus
References
1. Ragvin, A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(2):775-780 (2010). 2. Trynka, G., et al. Gut 58(8):1078-1083 (2009). 3. Lewis, M.T., et al. Cell Tissue Res. 296(3):549-554 (1999). 4. Bellefroid, E.J., et al. EMBO J. 17(1):191-203 (1998)