Caspase 3 (CPP-32, Apoptain, Yama, SCA-1) (Not for Export EU)
Cat# C2087-22J-200ul
Size : 200ul
Brand : US Biological
C2087-22J Caspase 3 (CPP-32, Apoptain, Yama, SCA-1) (Not for Export EU)
Clone Type
PolyclonalHost
rabbitSource
humanSwiss Prot
P42574Isotype
IgGGrade
SerumApplications
WBCrossreactivity
Bo Ca Ch Gp Hm Hu Mk Mo Po Rb Rt Sh XeShipping Temp
Blue IceStorage Temp
-20°CThe caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.||Applications: |Suitable for use Western Blot. Other applications not tested.||Recommended Dilutions:|Western Blot (ECL): 1:5000 detects a band at ~36kD|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.