Boc-Val-Pro-Arg-AMC
€ 267.50 – € 1,071.10
Pack size available | 50mg, 250mg |
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Please select pack size:
Product Description
Boc-VPR-AMC, a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. The thrombin assay has been used for the indirect determination of coagulation factor III. Trypsin, tryptase from rat mast cells, and two trypsin-like enzymes from sperm of the ascidian Halocynthia roretzi, acrosin and spermosin, also hydrolyze this substrate. Furthermore, Boc-VPR-AMC is cleaved by the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells. Kinetic data for Thrombin: kcat = 105, Km = 21 uM.
Substrates |
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Kexin |
Thrombin (Coagulation Factor IIa) |
Trypsin |
Tryptase |