Anti-VKORC1 antibody (10-60) {FITC}

Cat# NB-22-60319-100

Size : 100ug

Brand : Neo Biotech


General Info

Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-VKORC1 (10-60) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.65-0.70 µg/µl
Dilution Range: WB: 1:500
DB: 1:50, 000
ELISA: 1:50, 000
IP: 1:200
IHC: 1:250
ICC: 1:250
IF: 1:250
CFM: 1:250
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Information

Gene Symbol: Vkorc1
Gene ID: 309004
Uniprot ID: VKOR1_RAT
Immunogen Region: 10-60
Immunogen: Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.

Description

Tissue Specificity Highly expressed in liver. Detected at lower levels in lung, kidney and testis.
Function Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
Protein Name Vitamin K Epoxide Reductase Complex Subunit 1
Vitamin K1 2 -3-Epoxide Reductase Subunit 1
Database Links Reactome: R-RNO-6806664
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Vitamin K Epoxide Reductase Complex Subunit 1 antibody
Anti-Vitamin K1 2 -3-Epoxide Reductase Subunit 1 antibody
Anti-Vkorc1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance