The liver system plays an essential role in metabolism and produces digestive enzymes, synthesises hormones, stores bile and removes toxins. Hepatocytes, stellate cells, endothelial cells and fibroblasts are essential components required for the normal functioning of the liver and gallbladder. The liver is the largest organ in the human body. It is part of the digestive system and performs many functions that are vital to the body. The liver has multiple functions but the 3 main ones are purification, synthesis and storage. It is an amphicrine gland which allows the synthesis of bile (exocrine role) as well as that of several carbohydrates and lipids (endocrine role). It also plays an important role in haemostasis. It is a richly vascularised organ. Atypical cell proliferation and regulation within the liver system contribute to the development of liver diseases and cancers.