Transferrin (Beta-1 metal-binding globulin, Siderophilin) (HRP)
Cat# 145317-HRP-100ul
Size : 100ul
Brand : US Biological
145317-HRP Rabbit Anti-Transferrin (Beta-1 metal-binding globulin, Siderophilin) (HRP)
Clone Type
PolyclonalHost
rabbitSource
humanSwiss Prot
P02787Isotype
IgGGrade
Affinity PurifiedApplications
E IHC WBCrossreactivity
HuShipping Temp
Blue IceStorage Temp
-20°CTransferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. In humans, it is encoded by the TF gene. In humans, transferrin consists of a polypeptide chain containing 679 amino acids. The protein is composed of alpha helices and beta sheets to form two domains. The N- and C- terminal sequences are represented by globular lobes and between the two lobes is an iron-binding site. Transferrin is a glycoprotein that binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (1023 M−1 at pH 7.4) but decreases progressively with decreasing pH below neutrality.||UniProt Number:|P02787||Gene ID:|TF||Applications:|Suitable for use in ELISA, Western Blot and Immunohistochemistry (Paraffin).||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Handling:|Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term.|Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.