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> Ruxolitinib (Standard) [941678-49-5]

Ruxolitinib (Standard) [941678-49-5]

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Cat# HY-50856R-50mg

Size : 50mg

Brand : MedChemExpress

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Ruxolitinib (Standard) is the analytical standard of Ruxolitinib. This product is intended for research and analytical applications. Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.

For research use only. We do not sell to patients.

Ruxolitinib (Standard) Chemical Structure

Ruxolitinib (Standard) Chemical Structure

CAS No. : 941678-49-5

This product is a controlled substance and not for sale in your territory.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ruxolitinib (Standard)941678-49-5JAKAutophagyMitophagyApoptosisJanus kinaseMitochondrial AutophagyInhibitorinhibitorinhibit