Reagents and instruments for immunology, cell biology and molecular biology.

Ruxolitinib phosphate [1092939-17-7]

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Cat# A3781-1ml

Size : 10mM(in1mLDMSO)

Brand : APExBIO Technology

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Background

INCB018424 (Ruxolitinib) is an orally bioavailable JAK inhibitor .(IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively).INCB018424 is useful for rheumatoid arthritis.

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	404.36
Cas No.	1092939-17-7
Formula	C₁₇H₂₁N₆O₄P
Synonyms	INCB018424 phosphate;INCB 018424 phosphate;INCB-018424 phosphate;Ruxolitinib
Solubility	≥20.2 mg/mL in DMSO; ≥6.92 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.03 mg/mL in H2O with gentle warming and ultrasonic
Chemical Name	(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
SDF	Download SDF
Canonical SMILES	[HH].C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OOP(=O)=O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Purity = 99.87%