Reagents and instruments for immunology, cell biology and molecular biology.

Roundabout 4, NT (ROBO4, Roundabout homolog 4, Magic roundabout)

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Cat# 041170-200ul

Size : 200ul

Brand : US Biological

041170 Rabbit Anti-Roundabout 4, NT (ROBO4, Roundabout homolog 4, Magic roundabout)

Clone Type

Polyclonal

Host

rabbit

Source

human

Swiss Prot

Q8WZ75

Isotype

IgG

Grade

Affinity Purified

Applications

FC IHC WB

Crossreactivity

Gene #

ROBO4

Shipping Temp

Blue Ice

Storage Temp

-20°C

Roundabout 4 is receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. This protein may mediate the inhibition of primary endothelial cell migration by Slit proteins.||Applications:|Suitable for use in Western Blot, Immunohistochemistry and Indirect Flow Cytometry. Other applications not tested.||Recommended Dilution:|Western Blot: 1:1,000|Immunohistochemistry 1:50-100|Indirect Flow Cytometry: 1:10-50|Optimal dilution to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications

Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|Purity: Purified by Protein A affinity chromatography.|Immunogen: KLH-conjugated synthetic peptide corresponding to a portion of amino acids with corresponding to a portion of amino acids within aa236-264 in the N-terminal region of human Roundabout 4.|Specificity: Human||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Immunogen

KLH-conjugated synthetic peptide corresponding to a portion of amino acids with corresponding to a portion of amino acids within aa236-264 in the N-terminal region of human Roundabout 4.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Jones, C.A., et al. Nat. Cell Biol. 11(11):1325-1331(2009)|Sheldon, H., et al. FASEB J. 23(2):513-522(2009)|Huang, L., et al. Mol. Vis. 15, 1057-1069 (2009)