General Info
Applications: | ELISA |
Reactivity: | Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.068ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This PTGES Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | Ptges |
Gene ID: | 59103 |
Uniprot ID: | PTGES_RAT |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Description
Tissue Specificity | |
Post Translational Modifications | |
Function | Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Catalyzes also the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively. |
Protein Name | Prostaglandin E SynthaseMpges-1Glutathione Peroxidase PtgesGlutathione Transferase PtgesInducible Prostaglandin E SynthaseMicrosomal Prostaglandin E Synthase 1 |
Database Links | Reactome: R-RNO-2162123 |
Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear RegionColocalizes With Ptgs1/Cox-1 And Ptgs2/Cox-2 In The Perinuclear Compartment |
Alternative ELISA Names | Prostaglandin E Synthase ELISA kitMpges-1 ELISA kitGlutathione Peroxidase Ptges ELISA kitGlutathione Transferase Ptges ELISA kitInducible Prostaglandin E Synthase ELISA kitMicrosomal Prostaglandin E Synthase 1 ELISA kitPtges ELISA kitPges ELISA kitPig12 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance