PEG300 [25322-68-3]
Cat# HY-Y0873-50mL
Size : 50mL
Brand : MedChemExpress
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol.
For research use only. We do not sell to patients.
PEG300 Chemical Structure
CAS No. : 25322-68-3
This product is a controlled substance and not for sale in your territory.
Based on 80 publication(s) in Google Scholar
Other Forms of PEG300:
- PEG400 In-stock
- PEG1500 In-stock
- PEG200 In-stock
- PEG500 In-stock
- PEG3000 In-stock
- PEG10000 In-stock
- PEG20000 In-stock
Description |
PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol[1][2]. |
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In Vitro |
The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Molecular Weight |
300.00 |
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CAS No. |
25322-68-3 |
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Appearance |
Liquid (Density: 1.127 g/mL) |
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Color |
Colorless to light yellow |
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SMILES |
02OCCO02.9 |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvent & Solubility |
In Vitro:
DMSO : 100 mg/mL (333.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : ≥ 50 mg/mL (166.67 mM) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: ≥97.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O / DMSO | 1 mM | 3.3333 mL | 16.6667 mL | 33.3333 mL | 83.3333 mL |
5 mM | 0.6667 mL | 3.3333 mL | 6.6667 mL | 16.6667 mL | |
10 mM | 0.3333 mL | 1.6667 mL | 3.3333 mL | 8.3333 mL | |
15 mM | 0.2222 mL | 1.1111 mL | 2.2222 mL | 5.5556 mL | |
20 mM | 0.1667 mL | 0.8333 mL | 1.6667 mL | 4.1667 mL | |
25 mM | 0.1333 mL | 0.6667 mL | 1.3333 mL | 3.3333 mL | |
30 mM | 0.1111 mL | 0.5556 mL | 1.1111 mL | 2.7778 mL | |
40 mM | 0.0833 mL | 0.4167 mL | 0.8333 mL | 2.0833 mL | |
50 mM | 0.0667 mL | 0.3333 mL | 0.6667 mL | 1.6667 mL | |
60 mM | 0.0556 mL | 0.2778 mL | 0.5556 mL | 1.3889 mL | |
80 mM | 0.0417 mL | 0.2083 mL | 0.4167 mL | 1.0417 mL | |
100 mM | 0.0333 mL | 0.1667 mL | 0.3333 mL | 0.8333 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
PEG300 Related Classifications
- Others
- Others
- Biochemical Assay Reagents
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
PEG30025322-68-3Polyethylene glycol 300PEG 300PEG-300Polyethylene glycol300Polyethylene glycol-300Biochemical Assay ReagentsimmunogenicbiocompatiblepolymergastrointestinalmarkerInhibitorinhibitorinhibit