Human NTSR1 (Neurotensin Receptor 1, High Affinity) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	NTSR1
Gene ID:	4923
Uniprot ID:	NTR1_HUMAN
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
Post Translational Modifications	N-glycosylated. Palmitoylated.this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment.
Function	G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis.
Protein Name	Neurotensin Receptor Type 1 Nt-R-1 Ntr1 High-Affinity Levocabastine-Insensitive Neurotensin Receptor Ntrh
Database Links	Reactome: R-HSA-375276 Reactome: R-HSA-416476
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Membrane Raft Palmitoylation Is Required For Localization At Cav1-Enriched Membrane Rafts
Alternative ELISA Names	Neurotensin Receptor Type 1 ELISA kit Nt-R-1 ELISA kit Ntr1 ELISA kit High-Affinity Levocabastine-Insensitive Neurotensin Receptor ELISA kit Ntrh ELISA kit NTSR1 ELISA kit NTRR ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance