Duramycin [1391-36-2]
Cat# HY-106302-5mg
Size : 5mg
Brand : MedChemExpress
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF).
For research use only. We do not sell to patients.
Duramycin Chemical Structure
CAS No. : 1391-36-2
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Description |
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF)[1][2]. |
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In Vivo |
Evaluation of [68Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [68Ga]NODAGA-Duramycin. [68Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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Molecular Weight |
2013.28 |
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Formula |
C89H125N23O25S3 |
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CAS No. |
1391-36-2 |
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Appearance |
Solid |
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Color |
White to off-white |
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Sequence |
Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11) |
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Sequence Shortening |
CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11) |
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SMILES |
[CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)] |
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Initial Source |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
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Solvent & Solubility |
In Vitro:
H2O : 0.5 mg/mL (0.25 mM; Need ultrasonic)
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
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Purity & Documentation |
Purity: 99.46% |
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References |
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Duramycin Related Classifications
- Inflammation/Immunology Infection
- Anti-infection
- Bacterial