General Info
Host: | Mouse |
Applications: | FC/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-IgE is suitable for use in Flow Cytometry and ELISA research applications. |
Clonality: | Monoclonal |
Clone ID: | 4H10+ |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
Purification: | Purified by protein-A affinity chromatography. |
Concentration: | 1 mg/mL |
Storage Instruction: | Store at 2-8°C upon receipt. |
Information
Immunogen: | Purified human IgE. |
Description
Background | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days) , it is stabilized after binding to its high affinity receptor. Unlike IgM-IgG-and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance