Recombinant Human M-CSF

Macrophage colony-stimulating factor (M-CSF), also known as CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF enhances expression of differentiation antigens and stimulates chemotactic, phagocytic and the killing activities of monocytes. M-CSF also stimulates production of several cytokines, including GM- CSF, G-CSF and IL-6 by priming monocytes. It also stimulates production and secretion of IL-8 and reactive nitrogen intermediates. In addition to the stimulation of hematopoiesis, M-CSF also stimulates differentiation and proliferation of osteoclast progenitor cells and cytotrophoblasts.

Alternate Names - ​CSF1, CSF-1, MCSF, colony stimulating factor 1

Amino Acid Homology Across Species
Homo sapiens (human) M-CSF – 100%
Gorilla gorilla gorilla (western lowland gorilla) M-CSF – 100%
Chlorocebus sabaeus (green monkey) M-CSF – 100%
Colobus angolensis palliates M-CSF – 100%
Macaca mulatta (Rhesus monkey) M-CSF – 100%
Papio anubis (olive baboon) M-CSF – 100%
Piliocolobus tephrosceles (Ugandan red Colobus) M-CSF – 100%
Rhinopithecus roxellana (golden snub-nosed monkey) M-CSF – 100%
Theropithecus gelada (gelada) M-CSF – 100%
https://blast.ncbi.nlm.nih.gov