Rat ERb (Estrogen Receptor Beta) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Esr2
Gene ID:	25149
Uniprot ID:	ESR2_RAT
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in prostate, ovary, lung, liver, kidney, fat, bone, brain, uterus and testis.
Post Translational Modifications	Phosphorylation at Ser-87 and Ser-105 recruits NCOA1.
Function	Isoform 1: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform 2: Lacks ligand binding affinity and suppresses ESR1/ER-alpha and ESR2 isoform 1/ER-beta1 mediated transcriptional activation and may act as a dominant negative regulator of estrogen action. Isoform 3: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain. Isoform 4: Unable to bind DNA and activate transcription due to the truncation of the DNA binding domain.
Protein Name	Estrogen Receptor Beta Er-Beta Nuclear Receptor Subfamily 3 Group A Member 2
Database Links	Reactome: R-RNO-1257604 Reactome: -RNO-383280 Reactome: -RNO-6811558 Reactome: -RNO-8939211 Reactome: -RNO-9009391
Cellular Localisation	Nucleus
Alternative ELISA Names	Estrogen Receptor Beta ELISA kit Er-Beta ELISA kit Nuclear Receptor Subfamily 3 Group A Member 2 ELISA kit Esr2 ELISA kit Erbeta ELISA kit Nr3a2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance