Anti-SLC2A8 antibody (400-500) {FITC}

Cat# NB-22-58071-100

Size : 100ug

Brand : Neo Biotech


General Info

Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC2A8 (400-500) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.56-0.70 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Information

Gene Symbol: SLC2A8
Gene ID: 29988
Uniprot ID: SL2A8_HUMAN
Immunogen Region: 400-500
Immunogen: Synthetic peptide taken within amino acid region 400-500 on GLUT8 protein.

Description

Tissue Specificity Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Function Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate.
Protein Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8
Glucose Transporter Type 8
Glut-8
Glucose Transporter Type X1
Database Links Reactome: R-HSA-189200
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasmic Vesicle Membrane
Principally Intracellular
May Move Between Intracellular Vesicles And The Plasma Membrane
The Dileucine Internalization Motif Is Critical For Intracellular Sequestration
Alternative Antibody Names Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 antibody
Anti-Glucose Transporter Type 8 antibody
Anti-Glut-8 antibody
Anti-Glucose Transporter Type X1 antibody
Anti-SLC2A8 antibody
Anti-GLUT8 antibody
Anti-GLUTX1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance