General Info
Host: | Rabbit |
Applications: | ELISA/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-SLC2A8 (400-500) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | FITC |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.56-0.70 µg/µl |
Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
Gene Symbol: | SLC2A8 |
Gene ID: | 29988 |
Uniprot ID: | SL2A8_HUMAN |
Immunogen Region: | 400-500 |
Immunogen: | Synthetic peptide taken within amino acid region 400-500 on GLUT8 protein. |
Description
Tissue Specificity | Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues. |
Function | Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. |
Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8Glucose Transporter Type 8Glut-8Glucose Transporter Type X1 |
Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePrincipally IntracellularMay Move Between Intracellular Vesicles And The Plasma MembraneThe Dileucine Internalization Motif Is Critical For Intracellular Sequestration |
Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 8 antibodyAnti-Glucose Transporter Type 8 antibodyAnti-Glut-8 antibodyAnti-Glucose Transporter Type X1 antibodyAnti-SLC2A8 antibodyAnti-GLUT8 antibodyAnti-GLUTX1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance