Anti-FPR1 antibody (150-200) {Biotin}

Clonality:	Polyclonal
Conjugation:	Biotin
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	FPR1
Gene ID:	2357
Uniprot ID:	FPR1_HUMAN
Immunogen Region:	150-200
Immunogen:	Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.

Tissue Specificity	Neutrophils.
Post Translational Modifications	Phosphorylated.which is necessary for desensitization.
Function	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Protein Name	Fmet-Leu-Phe Receptor Fmlp Receptor N-Formyl Peptide Receptor Fpr N-Formylpeptide Chemoattractant Receptor
Database Links	Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Internalizes In Presence Of Its Ligands Fmlp Tafa4 And Ctsg
Alternative Antibody Names	Anti-Fmet-Leu-Phe Receptor antibody Anti-Fmlp Receptor antibody Anti-N-Formyl Peptide Receptor antibody Anti-Fpr antibody Anti-N-Formylpeptide Chemoattractant Receptor antibody Anti-FPR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance