OGG1 (NM_016821) Human Recombinant Protein
Cat# TP760967
Size : 50ug
OGG1 (NM_016821) Human Recombinant Protein
SKU
TP760967
Purified recombinant protein of Human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
In Stock*
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence | Protein Sequence A DNA sequence encoding human full-length OGG1 |
| Tag | N-His |
| Predicted MW | 47.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_058214 |
| Locus ID | 4968 |
| UniProt ID | O15527 |
| Cytogenetics | 3p25.3 |
| RefSeq Size | 2108 |
| RefSeq ORF | 1272 |
| Synonyms | HMMH; HOGG1; MUTM; OGH1 |
| Summary | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
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Recombinant Protein Resources |
| SKU | Description | Size | ||
|---|---|---|---|---|
| LC413811 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC413813 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC413815 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC413816 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC413835 | OGG1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LY413811 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2a | 100 ug | | |
| LY413813 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2b | 100 ug | | |
| LY413815 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2d | 100 ug | | |
| LY413816 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 2e | 100 ug | | |
| LY413835 | Transient overexpression lysate of 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1b | 100 ug | | |
| TP720109 | Recombinant protein of human 8-oxoguanine DNA glycosylase (OGG1), nuclear gene encoding mitochondrial protein, transcript variant 1a | 10 ug | | |
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